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Image Search Results
Journal: Oncotarget
Article Title: Silencing of casein kinase 1 delta reduces migration and metastasis of triple negative breast cancer cells
doi: 10.18632/oncotarget.25738
Figure Lengend Snippet: ( A ) Scatter plot of gene expression analysis by RT 2 Profiler PCR Array in the shNT MDA-MB-231 cells compared to shCSNK1D cells. The central line indicates unchanged gene expression. ( B ) Taqman validation of genes identified in the RT Profiler array. The histogram represents fold change of genes up-or down-regulated in shCSNK1D compared to shNT control cells. ( C ) Western blot analysis of the expression of occludin (OCLN), junction adhesion molecule A (F11R) and claudin-1 (CLDN-1) in control (shNT) and inactivated cell lines (shCSNK1D). ( D ) Detection of OCLN and F11R by immunofluorescence in shCSNK1D compared to control shNT cells. Nuclei were stained with Dapi. Arrows indicate the increased expression of tight junction proteins.
Article Snippet: After washing, the cells were mounted with
Techniques: Gene Expression, Biomarker Discovery, Control, Western Blot, Expressing, Immunofluorescence, Staining